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A parsimonious model for gene regulation by miRNAs
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) act in complex with the Argonaute family of proteins to regulate target messenger RNAs (mRNAs) post transcriptionally. SiRNAs typically induce endonucleolytic cleavage of mRNA with near-perfect complementarity. For targets with less complementar...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3955125/ https://ncbi.nlm.nih.gov/pubmed/21292970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191138 |
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