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A parsimonious model for gene regulation by miRNAs

MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) act in complex with the Argonaute family of proteins to regulate target messenger RNAs (mRNAs) post transcriptionally. SiRNAs typically induce endonucleolytic cleavage of mRNA with near-perfect complementarity. For targets with less complementar...

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Bibliografiska uppgifter
Huvudupphovsmän: Djuranovic, Sergej, Nahvi, Ali, Green, Rachel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955125/
https://ncbi.nlm.nih.gov/pubmed/21292970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191138
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