Simultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer

Development of cisplatin-resistance is an obstacle in non-small cell lung cancer (NSCLC) therapeutics. To investigate which molecules are associated with cisplatin-resistance, we analyzed expression profiles of several DNA repair and anti-apoptosis associated molecules in parental (A549P and H157P)...

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Publicat a:Cancer Biol Ther
Autors principals: Zhang, Fuquan, Shen, Mingjing, Yang, Li, Yang, Xiaodong, Tsai, Ying, Keng, Peter C., Chen, Yongbing, Lee, Soo Ok, Chen, Yuhchyau
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653185/
https://ncbi.nlm.nih.gov/pubmed/28686074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1345391
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