A FASN-TGF-β1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer

Cisplatin-resistant A549CisR and H157CisR cell lines were developed by treating parental A549 (A549P) and H157 (H157P) cells. These cisplatin-resistant cells showed slight growth retardation, but exhibited higher epithelial-mesenchymal transition (EMT) and increased metastatic potential compared to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Li, Zhang, Fuquan, Wang, Xin, Tsai, Ying, Chuang, Kuang-Hsiang, Keng, Peter C., Lee, Soo Ok, Chen, Yuhchyau
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342435/
https://ncbi.nlm.nih.gov/pubmed/27765901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10837
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