TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear

In contrast to TP53, cancer development is rarely associated with mutations in the TP63 and TP73 genes. Recently, next generation sequencing analysis revealed that TP63 mutations are frequent, specifically in cutaneous melanomas. Cutaneous melanoma represents 4% of skin cancers but it is responsible...

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Vydáno v:Oncol Rep
Hlavní autoři: Monti, Paola, Ghiorzo, Paola, Menichini, Paola, Foggetti, Giorgia, Queirolo, Paola, Izzotti, Alberto, Fronza, Gilberto
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652947/
https://ncbi.nlm.nih.gov/pubmed/28849221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5903
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