SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation

Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα pr...

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Vydáno v:Oncotarget
Hlavní autoři: Zhuang, Ting, Yu, Sifan, Zhang, Lichen, Yang, Huijie, Li, Xin, Hou, Yingxiang, Liu, Zhenhua, Shi, Yuanyuan, Wang, Weilong, Yu, Na, Li, Anqi, Li, Xuefeng, Li, Xiumin, Niu, Gang, Xu, Juntao, Hasni, Muhammad Sharif, Mu, Kun, Wang, Hui, Zhu, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652769/
https://ncbi.nlm.nih.gov/pubmed/29100376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20368
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