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SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation
Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα pr...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652769/ https://ncbi.nlm.nih.gov/pubmed/29100376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20368 |
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