SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation

Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα pr...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Zhuang, Ting, Yu, Sifan, Zhang, Lichen, Yang, Huijie, Li, Xin, Hou, Yingxiang, Liu, Zhenhua, Shi, Yuanyuan, Wang, Weilong, Yu, Na, Li, Anqi, Li, Xuefeng, Li, Xiumin, Niu, Gang, Xu, Juntao, Hasni, Muhammad Sharif, Mu, Kun, Wang, Hui, Zhu, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652769/
https://ncbi.nlm.nih.gov/pubmed/29100376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20368
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