SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation

Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα pr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhuang, Ting, Yu, Sifan, Zhang, Lichen, Yang, Huijie, Li, Xin, Hou, Yingxiang, Liu, Zhenhua, Shi, Yuanyuan, Wang, Weilong, Yu, Na, Li, Anqi, Li, Xuefeng, Li, Xiumin, Niu, Gang, Xu, Juntao, Hasni, Muhammad Sharif, Mu, Kun, Wang, Hui, Zhu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652769/
https://ncbi.nlm.nih.gov/pubmed/29100376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20368
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