Pancreatic β-Cell–Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation

Pancreatic islets produce and secrete cytokines and chemokines in response to inflammatory and metabolic stress. The physiological role of these “isletokines” in health and disease is largely unknown. We observed that islets release multiple inflammatory mediators in patients undergoing islet transp...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Yoshimatsu, Gumpei, Kunnathodi, Faisal, Saravanan, Prathab Balaji, Shahbazov, Rauf, Chang, Charles, Darden, Carly M., Zurawski, Sandra, Boyuk, Gulbahar, Kanak, Mazhar A., Levy, Marlon F., Naziruddin, Bashoo, Lawrence, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652609/
https://ncbi.nlm.nih.gov/pubmed/28855240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0578
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