Alleviation of Instant Blood-Mediated Inflammatory Reaction in Autologous Conditions through Treatment of Human Islets with NF-κB Inhibitors

BACKGROUND: The instant blood-mediated inflammatory response (IBMIR) has been shown as a major factor that causes damage to transplanted islets. Withaferin A (WA), an inhibitor of nuclear factor κB (NFκB), was shown to suppress the inflammatory response in islets and improve syngeneic islet graft su...

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Autori principali: Kanak, Mazhar A., Takita, Morihito, Itoh, Takeshi, SoRelle, Jeffrey A., Murali, Shyam, Kunnathodi, Faisal, Shahbazov, Rauf, Lawrence, Michael C., Levy, Marlon F., Naziruddin, Bashoo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206260/
https://ncbi.nlm.nih.gov/pubmed/24798306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000107
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