Pancreatic β-Cell–Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation

Pancreatic islets produce and secrete cytokines and chemokines in response to inflammatory and metabolic stress. The physiological role of these “isletokines” in health and disease is largely unknown. We observed that islets release multiple inflammatory mediators in patients undergoing islet transp...

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Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Yoshimatsu, Gumpei, Kunnathodi, Faisal, Saravanan, Prathab Balaji, Shahbazov, Rauf, Chang, Charles, Darden, Carly M., Zurawski, Sandra, Boyuk, Gulbahar, Kanak, Mazhar A., Levy, Marlon F., Naziruddin, Bashoo, Lawrence, Michael C.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2017
Matèries:
Immunology and Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652609/
https://ncbi.nlm.nih.gov/pubmed/28855240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0578
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