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Crystal structure of an inactivated mutant mammalian voltage-gated K(+) channel

C-type inactivation underlies important roles played by voltage-gated K(+) (Kv) channels. Functional studies have provided strong evidence that a common underlying cause of this type of inactivation is an alteration near the extracellular end of the channel's ion selectivity filter. Unlike N-ty...

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Библиографические подробности
Опубликовано в: :Nat Struct Mol Biol
Главные авторы: Pau, Victor, Zhou, Yufeng, Ramu, Yajamana, Xu, Yanping, Lu, Zhe
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652298/
https://ncbi.nlm.nih.gov/pubmed/28846092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3457
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