IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk

BACKGROUND: IRX3 was recently reported as the effector of the FTO variants. We aimed to test IRX3's roles in the browning program and to evaluate the association between the genetic variants in IRX3 and human obesity. METHODS: IRX3 expression was examined in beige adipocytes in human and mouse...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Zou, Yaoyu, Lu, Peng, Shi, Juan, Liu, Wen, Yang, Minglan, Zhao, Shaoqian, Chen, Na, Chen, Maopei, Sun, Yingkai, Gao, Aibo, Chen, Qingbo, Zhang, Zhiguo, Ma, Qinyun, Ning, Tinglu, Ying, Xiayang, Jin, Jiabin, Deng, Xiaxing, Shen, Baiyong, Zhang, Yifei, Yuan, Bo, Kauderer, Sophie, Liu, Simin, Hong, Jie, Liu, Ruixin, Ning, Guang, Wang, Weiqing, Gu, Weiqiong, Wang, Jiqiu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652024/
https://ncbi.nlm.nih.gov/pubmed/28988979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.09.010
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