Blocking FSH Induces Thermogenic Adipose Tissue and Reduces Body Fat

Menopause is associated with bone loss and enhanced visceral adiposity. We have shown previously that a polyclonal antibody (Ab) to the β-subunit of the pituitary hormone Fsh increases bone mass in mice. Here, we report that this Ab sharply reduces adipose tissue in wild type mice, phenocopying gene...

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Argitaratua izan da:Nature
Egile Nagusiak: Liu, Peng, Ji, Yaoting, Yuen, Tony, Rendina-Ruedy, Elizabeth, DeMambro, Victoria E., Dhawan, Samarth, Abu-Amer, Wahid, Izadmehr, Sudeh, Zhou, Bin, Shin, Andrew, Latif, Rauf, Thangeswaran, Priyanthan, Gupta, Animesh, Li, Jianhua, Shnayder, Valeria, Robinson, Samuel T., Yu, Yue Eric, Zhang, Xingjian, Yang, Feiran, Lu, Ping, Zhou, Yu, Zhu, Ling-Ling, Oberlin, Douglas J., Davies, Terry F., Reagan, Michaela R., Brown, Aaron, Kumar, T. Rajendra, Epstein, Solomon, Iqbal, Jameel, New, Maria I., Molina, Henrik, van Klinken, Jan B., Guo, Edward X., Buettner, Christoph, Haider, Shozeb, Bian, Zhuan, Sun, Li, Rosen, Clifford J., Zaidi, Mone
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
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Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651981/
https://ncbi.nlm.nih.gov/pubmed/28538730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22342
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