Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice

Aims: Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive motor deficits and degeneration of dopaminergic neurons. Caused by a number of genetic and environmental factors, mitochondrial dysfunction and oxidative stress play a role in neurodegeneration in PD. By...

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Dades bibliogràfiques
Publicat a:Antioxid Redox Signal
Autors principals: Langley, Monica, Ghosh, Anamitra, Charli, Adhithiya, Sarkar, Souvarish, Ay, Muhammet, Luo, Jie, Zielonka, Jacek, Brenza, Timothy, Bennett, Brian, Jin, Huajun, Ghaisas, Shivani, Schlichtmann, Benjamin, Kim, Dongsuk, Anantharam, Vellareddy, Kanthasamy, Arthi, Narasimhan, Balaji, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2017
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651937/
https://ncbi.nlm.nih.gov/pubmed/28375739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6905
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