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Munc18a Clusters SNARE-Bearing Liposomes Prior to Trans-SNARE Zippering

Sec1-Munc18 (SM) proteins cooperate with SNAREs {SNAP [soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein] receptors} to mediate membrane fusion in eukaryotic cells. Studies of Munc18a/Munc18-1/Stxbp1 in neurotransmission suggest that SM proteins accelerate fusion kinetics primarily...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem J
Prif Awduron: Arnold, Matthew Grant, Adhikari, Pratikshya, Kang, Baobin, Xu (徐昊), Hao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651683/
https://ncbi.nlm.nih.gov/pubmed/28827281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170494
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