Estrogen receptor β exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NF-kB/BCL-2 and PI3K/Akt signal pathway

This study aimed to investigate the effects of Estrogen receptor β (ERβ) on osteosarcoma cells, and explore the regulatory mechanisms involved in this process. Osteosarcoma U2-OS cells consisted four groups, and treated by E2, E2 + LY294002 (ERβ agonists), E2 + ERβ siRNA, E2 + ERβ siRNA + LY294002,...

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Detalles Bibliográficos
Publicado en:J Bone Oncol
Autores principales: Yang, Minfei, Liu, Bing, Jin, Libin, Tao, Huimin, Yang, Zhengming
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651467/
https://ncbi.nlm.nih.gov/pubmed/29071206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2017.09.005
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