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Quantitative disease progression model of α‐1 proteinase inhibitor therapy on computed tomography lung density in patients with α‐1 antitrypsin deficiency
AIMS: Early‐onset emphysema attributed to α‐1 antitrypsin deficiency (AATD) is frequently overlooked and undertreated. RAPID‐RCT/RAPID‐OLE, the largest clinical trials of purified human α‐1 proteinase inhibitor (A(1)‐PI; 60 mg kg(–1) week(–1)) therapy completed to date, demonstrated for the first ti...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651313/ https://ncbi.nlm.nih.gov/pubmed/28662542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13358 |
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