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Leptin Status Alters Buprenorphine-Induced Antinociception in Obese Mice with Dysfunctional Leptin Receptors

Buprenorphine is an opiate used for pain management and to treat opiate addiction. The cytokine leptin can modulate nociception, but the extent to which buprenorphine-induced antinociception varies as a function of leptin signaling has not been characterized. Four congenic mouse lines with phenotype...

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Bibliographic Details
Published in:Neurosci Lett
Main Authors: Glovak, Zachary, Mihalko, Sara, Baghdoyan, Helen A., Lydic, Ralph
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651198/
https://ncbi.nlm.nih.gov/pubmed/28893589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2017.09.012
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