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Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics
The immune system produces a diverse repertoire of immunoglobulins in response to foreign antigens. During B-cell development, VDJ recombination and somatic mutations generate diversity, whereas selection processes remove it. Using both proteomic and NGS approaches, we characterized the immune reper...
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Publicado no: | Front Immunol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650670/ https://ncbi.nlm.nih.gov/pubmed/29085363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01286 |
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