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Next-Generation Sequencing of Antibody Display Repertoires

In vitro selection technology has transformed the development of therapeutic monoclonal antibodies. Using methods such as phage, ribosome, and yeast display, high affinity binders can be selected from diverse repertoires. Here, we review strategies for the next-generation sequencing (NGS) of phage-...

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Publicat a:Front Immunol
Autors principals: Rouet, Romain, Jackson, Katherine J. L., Langley, David B., Christ, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810246/
https://ncbi.nlm.nih.gov/pubmed/29472918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00118
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