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Next-Generation Sequencing of Antibody Display Repertoires

In vitro selection technology has transformed the development of therapeutic monoclonal antibodies. Using methods such as phage, ribosome, and yeast display, high affinity binders can be selected from diverse repertoires. Here, we review strategies for the next-generation sequencing (NGS) of phage-...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rouet, Romain, Jackson, Katherine J. L., Langley, David B., Christ, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810246/
https://ncbi.nlm.nih.gov/pubmed/29472918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00118
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