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An antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions

Autoantibodies are increasingly used as biomarkers in the detection of autoimmune disorders and cancer. Disease specific antibodies are generally detected by their binding to specific antigens. As an alternative approach, we propose to identify specific complementarity determining regions (CDR) of I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dekker, Lennard J. M., Zeneyedpour, Lona, Brouwer, Eric, van Duijn, Martijn M., Sillevis Smitt, Peter A. E., Luider, Theo M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer-Verlag 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018266/
https://ncbi.nlm.nih.gov/pubmed/21107826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-4361-9
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