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An antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions
Autoantibodies are increasingly used as biomarkers in the detection of autoimmune disorders and cancer. Disease specific antibodies are generally detected by their binding to specific antigens. As an alternative approach, we propose to identify specific complementarity determining regions (CDR) of I...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018266/ https://ncbi.nlm.nih.gov/pubmed/21107826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-4361-9 |
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