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An antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions

Autoantibodies are increasingly used as biomarkers in the detection of autoimmune disorders and cancer. Disease specific antibodies are generally detected by their binding to specific antigens. As an alternative approach, we propose to identify specific complementarity determining regions (CDR) of I...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Dekker, Lennard J. M., Zeneyedpour, Lona, Brouwer, Eric, van Duijn, Martijn M., Sillevis Smitt, Peter A. E., Luider, Theo M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018266/
https://ncbi.nlm.nih.gov/pubmed/21107826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-4361-9
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