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Hypoxia negates hyperglycaemia-induced chemo-resistance in breast cancer cells: the role of insulin-like growth factor binding protein 2

BACKGROUND: Women who suffer from breast cancer and type II diabetes with associated hyperglycaemia respond less well to chemotherapy. We have shown that hyperglycaemia induces resistance to chemotherapy through upregulation of fatty acid synthase (FASN) in breast cancer cells and increased insulin-...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Al Qahtani, Athba, Holly, Jeff, Perks, Claire
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650368/
https://ncbi.nlm.nih.gov/pubmed/29088813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20287
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