Immunohistochemical expression of insulin-like growth factor binding protein-3 in invasive breast cancers and ductal carcinoma in situ: implications for clinicopathology and patient outcome

INTRODUCTION: Insulin-like growth factor binding protein-3 (IGFBP-3) differentially modulates breast epithelial cell growth through insulin-like growth factor (IGF)-dependent and IGF-independent pathways and is a direct (IGF-independent) growth inhibitor as well as a mitogen that potentiates EGF (ep...

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Detalhes bibliográficos
Main Authors: Vestey, Sarah B, Perks, Claire M, Sen, Chandan, Calder, Caroline J, Holly, Jeff MP, Winters, Zoe E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064109/
https://ncbi.nlm.nih.gov/pubmed/15642160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr963
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