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Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation

Epidermal squamous cell carcinoma (SCC) is among the most common cancers. SCC can be treated by surgical excision, but recurrence of therapy-resistant disease is a major problem. We recently showed that YAP1, the Hippo signaling transcription adaptor protein, and ∆Np63α, a key epidermal stem cell su...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fisher, Matthew L., Ciavattone, Nicholas, Grun, Daniel, Adhikary, Gautam, Eckert, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650271/
https://ncbi.nlm.nih.gov/pubmed/29088716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20562
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