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Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation

Epidermal squamous cell carcinoma (SCC) is among the most common cancers. SCC can be treated by surgical excision, but recurrence of therapy-resistant disease is a major problem. We recently showed that YAP1, the Hippo signaling transcription adaptor protein, and ∆Np63α, a key epidermal stem cell su...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Fisher, Matthew L., Ciavattone, Nicholas, Grun, Daniel, Adhikary, Gautam, Eckert, Richard L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650271/
https://ncbi.nlm.nih.gov/pubmed/29088716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20562
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