Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells

M3 muscarinic receptor (M3R) expression is increased in colon cancer; M3R activation stimulates colon cancer cell invasion via cross-talk with epidermal growth factor receptors (EGFR), post-EGFR activation of mitogen-activated protein kinase (MAPK) ERK1/2, and induction of matrix metalloproteinase-1...

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Bibliographic Details
Published in:Biochem J
Main Authors: Said, Anan H., Hu, Shien, Abutaleb, Ameer, Watkins, Tonya, Cheng, Kunrong, Chahdi, Ahmed, Kuppusamy, Panjamurthy, Saxena, Neeraj, Xie, Guofeng, Raufman, Jean-Pierre
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650067/
https://ncbi.nlm.nih.gov/pubmed/28008134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160704
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