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Asymmetric Protonation of Cumulenolates: Synthesis of Allenyl Aldehydes Facilitated by an Organomanganese Auxiliary

Chiral ammonium salts were used to catalyze the isomerization of organomanganese-complexed alkynyl aldehydes to chiral allenal building blocks in moderate to good enantiomeric excesses. Normally, conjugated alkynyl aldehydes do not isomerize to their thermodynamically less stable allene isomers. How...

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Détails bibliographiques
Publié dans:Org Lett
Auteurs principaux: Roy, Animesh, Bhat, Bilal A., Lepore, Salvatore D.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649623/
https://ncbi.nlm.nih.gov/pubmed/26925611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b03681
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