A systems biology approach identifies FUT8 as a driver of melanoma metastasis

Association of aberrant glycosylation with melanoma progression is based mainly on analyses of cell lines. Here we present a systems-based study of glycomic changes and corresponding enzymes associated with melanoma metastasis in patient samples. Upregulation of core fucosylation (FUT8) and downregu...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Agrawal, Praveen, Fontanals-Cirera, Barbara, Sokolova, Elena, Jacob, Samson, Vaiana, Christopher A., Argibay, Diana, Davalos, Veronica, McDermott, Meagan, Nayak, Shruti, Darvishian, Farbod, Castillo, Mireia, Ueberheide, Beatrix, Osman, Iman, Fenyö, David, Mahal, Lara K., Hernando, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649440/
https://ncbi.nlm.nih.gov/pubmed/28609658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.05.007
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