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Toll-Like Receptor-4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma

Significance: This review provides current overview of the emerging role of innate immunity in driving fibrosis, and preventing its resolution, in scleroderma (systemic sclerosis, SSc). Understanding the mechanisms of dysregulated innate immunity in fibrosis and SSc will provide opportunities for th...

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Detalhes bibliográficos
Publicado no:Adv Wound Care (New Rochelle)
Main Authors: Bhattacharyya, Swati, Midwood, Kim S., Yin, Hang, Varga, John
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649394/
https://ncbi.nlm.nih.gov/pubmed/29062592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/wound.2017.0732
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