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Toll-Like Receptor-4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma

Significance: This review provides current overview of the emerging role of innate immunity in driving fibrosis, and preventing its resolution, in scleroderma (systemic sclerosis, SSc). Understanding the mechanisms of dysregulated innate immunity in fibrosis and SSc will provide opportunities for th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Adv Wound Care (New Rochelle)
Prif Awduron: Bhattacharyya, Swati, Midwood, Kim S., Yin, Hang, Varga, John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649394/
https://ncbi.nlm.nih.gov/pubmed/29062592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/wound.2017.0732
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