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Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4
Malaria, caused by the protozoan Plasmodium is a devastating mosquito-borne disease, that puts nearly half the world’s population at risk(1). Despite mounting substantial T and B cell responses, humans fail to efficiently control blood-stage malaria or develop sterilizing immunity to reinfections(2)...
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| Vydáno v: | Nat Med |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5649372/ https://ncbi.nlm.nih.gov/pubmed/28892065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4395 |
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