A method to reduce ancestry related germline false positives in tumor only somatic variant calling

BACKGROUND: Significant clinical and research applications are driving large scale adoption of individualized tumor sequencing in cancer in order to identify tumors-specific mutations. When a matched germline sample is available, somatic mutations may be identified using comparative callers. However...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Halperin, Rebecca F., Carpten, John D., Manojlovic, Zarko, Aldrich, Jessica, Keats, Jonathan, Byron, Sara, Liang, Winnie S., Russell, Megan, Enriquez, Daniel, Claasen, Ana, Cherni, Irene, Awuah, Baffour, Oppong, Joseph, Wicha, Max S., Newman, Lisa A., Jaigge, Evelyn, Kim, Seungchan, Craig, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649057/
https://ncbi.nlm.nih.gov/pubmed/29052513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-017-0296-8
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