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Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the Airways

In infants, Bordetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hypertension, and even death. The exact cause of death remains unknown, and no effective therapies for treating fulminant pertussis exist. In this study, a neonatal mouse model of critical per...

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Publicado en:Infect Immun
Autores principales: Scanlon, Karen M., Snyder, Yael G., Skerry, Ciaran, Carbonetti, Nicholas H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649019/
https://ncbi.nlm.nih.gov/pubmed/28784932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00355-17
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