Pertussis Toxin Targets Airway Macrophages To Promote Bordetella pertussis Infection of the Respiratory Tract

Pertussis toxin (PT), a secreted virulence factor of Bordetella pertussis, ADP ribosylates mammalian G(i) proteins and plays an important early role in respiratory tract infection by this pathogen in a mouse intranasal infection model. To test the hypothesis that PT targets resident airway macrophag...

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Bibliographische Detailangaben
Hauptverfasser: Carbonetti, Nicholas H., Artamonova, Galina V., Van Rooijen, Nico, Ayala, Victor I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Bacterial Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865687/
https://ncbi.nlm.nih.gov/pubmed/17242062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01578-06
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