Reduction of Pertussis Inflammatory Pathology by Therapeutic Treatment With Sphingosine-1-Phosphate Receptor Ligands by a Pertussis Toxin-Insensitive Mechanism

Recent data have demonstrated the potential of sphingosine 1-phosphate (S1P) receptor (S1PR) agonism in the treatment of infectious diseases. A previous study used a murine model of Bordetella pertussis infection to demonstrate that treatment with the S1PR agonist AAL-R reduces pulmonary inflammatio...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Skerry, Ciaran, Scanlon, Karen, Ardanuy, Jeremy, Roberts, Drew, Zhang, Li, Rosen, Hugh, Carbonetti, Nicholas H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853922/
https://ncbi.nlm.nih.gov/pubmed/27815382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw536
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