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Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers
Store-operated calcium entry (SOCE) is a major pathway for calcium ions influx into cells and has a critical role in various cell functions. Here we demonstrate that calcium-bound calmodulin (Ca(2+)-CaM) binds to the core region of activated STIM1. This interaction facilitates slow Ca(2+)-dependent...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648805/ https://ncbi.nlm.nih.gov/pubmed/29051492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01135-w |
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