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Metabolic control by sirtuins and other enzymes that sense NAD(+), NADH, or their ratio

NAD(+) is a dinucleotide cofactor with the potential to accept electrons in a variety of cellular reduction-oxidation (redox) reactions. In its reduced form, NADH is a ubiquitous cellular electron donor. NAD(+), NADH, and the NAD(+)/NADH ratio have long been known to control the activity of several...

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Библиографические подробности
Опубликовано в: :Biochim Biophys Acta
Главные авторы: Anderson, Kristin A., Madsen, Andreas S., Olsen, Christian A., Hirschey, Matthew D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648639/
https://ncbi.nlm.nih.gov/pubmed/28947253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2017.09.005
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