Mouse embryonic stem cells can differentiate via multiple paths to the same state

In embryonic development, cells differentiate through stereotypical sequences of intermediate states to generate particular mature fates. By contrast, driving differentiation by ectopically expressing terminal transcription factors (direct programming) can generate similar fates by alternative route...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Briggs, James Alexander, Li, Victor C, Lee, Seungkyu, Woolf, Clifford J, Klein, Allon, Kirschner, Marc W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2017
Konular:
Stem Cells and Regenerative Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648529/
https://ncbi.nlm.nih.gov/pubmed/28990928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26945
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