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Mouse embryonic stem cells can differentiate via multiple paths to the same state
In embryonic development, cells differentiate through stereotypical sequences of intermediate states to generate particular mature fates. By contrast, driving differentiation by ectopically expressing terminal transcription factors (direct programming) can generate similar fates by alternative route...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648529/ https://ncbi.nlm.nih.gov/pubmed/28990928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26945 |
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