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Combinatorial microenvironments impose a continuum of cellular responses to a single pathway-targeted anti-cancer compound
Tumor microenvironments are a driver of resistance to anti-cancer drugs. Dissecting cell-microenvironment interactions into tractable units of study presents a challenge. Here, we assess the impact of hundreds of tumor-inspired microenvironments in parallel on lapatinib responses in four cancer cell...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648071/ https://ncbi.nlm.nih.gov/pubmed/29020637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.058 |
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