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Combinatorial microenvironments impose a continuum of cellular responses to a single pathway-targeted anti-cancer compound

Tumor microenvironments are a driver of resistance to anti-cancer drugs. Dissecting cell-microenvironment interactions into tractable units of study presents a challenge. Here, we assess the impact of hundreds of tumor-inspired microenvironments in parallel on lapatinib responses in four cancer cell...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Lin, Chun-Han, Jokela, Tiina, Gray, Joe, LaBarge, Mark A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648071/
https://ncbi.nlm.nih.gov/pubmed/29020637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.058
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