Combinatorial microenvironments impose a continuum of cellular responses to a single pathway-targeted anti-cancer compound

Por Lin, Chun-Han, Jokela, Tiina, Gray, Joe, LaBarge, Mark A
Publicado no Cell Rep (2017)

Interleukin-1β-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesi...

Por Jokela, Tiina, Oikari, Sanna, Takabe, Piia, Rilla, Kirsi, Kärnä, Riikka, Tammi, Markku, Tammi, Raija
Publicado no J Biol Chem (2015)

Extracellular UDP-Glucose Activates P2Y(14) Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr(705) Phosphorylation and Binding to Hyaluronan Synth...

Por Jokela, Tiina A., Kärnä, Riikka, Makkonen, Katri M., Laitinen, Jarmo T., Tammi, Raija H., Tammi, Markku I.
Publicado em 2014

Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3

Por Rilla, Kirsi, Oikari, Sanna, Jokela, Tiina A., Hyttinen, Juha M. T., Kärnä, Riikka, Tammi, Raija H., Tammi, Markku I.
Publicado em 2013

Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis

Por Jokela, Tiina, Kärnä, Riikka, Rauhala, Leena, Bart, Genevieve, Pasonen-Seppänen, Sanna, Oikari, Sanna, Tammi, Markku I., Tammi, Raija H.
Publicado no J Biol Chem (2017)

Cellular Content of UDP-N-acetylhexosamines Controls Hyaluronan Synthase 2 Expression and Correlates with O-Linked N-Acetylglucosamine Modification of Transcription Factors YY1 and...

Por Jokela, Tiina A., Makkonen, Katri M., Oikari, Sanna, Kärnä, Riikka, Koli, Elina, Hart, Gerald W., Tammi, Raija H., Carlberg, Carsten, Tammi, Markku I.
Publicado em 2011

Age-related dysfunction in mechano-transduction impairs differentiation of human mammary epithelial progenitors

Por Pelissier, Fanny A., Garbe, James C., Ananthanarayanan, Badriprasad, Miyano, Masaru, Lin, ChunHan, Jokela, Tiina, Kumar, Sanjay, Stampfer, Martha R., Lorens, James B., LaBarge, Mark A.
Publicado em 2014

Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analog reduces angiogenesis

Por van Wijk, Xander M., Thijssen, Victor L., Lawrence, Roger, van den Broek, Sebastiaan A., Dona, Margo, Naidu, Natasha, Oosterhof, Arie, van de Westerlo, Els M., Kusters, Lisanne J., Khaled, Yasmine, Jokela, Tiina A., Nowak-Sliwinska, Patrycja, Kremer, Hannie, Stringer, Sally E., Griffioen, Arjan W., van Wijk, Erwin, van Delft, Floris L., van Kuppevelt, Toin H.
Publicado em 2013