Extracellular UDP-Glucose Activates P2Y(14) Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr(705) Phosphorylation and Binding to Hyaluronan Synthase 2 (HAS2) Promoter, Stimulating Hyaluronan Synthesis of Keratinocytes

Hyaluronan, a major matrix molecule in epidermis, is often increased by stimuli that enhance keratinocyte proliferation and migration. We found that small amounts of UDP-sugars were released from keratinocytes and that UDP-glucose (UDP-Glc) added into keratinocyte cultures induced a specific, rapid...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jokela, Tiina A., Kärnä, Riikka, Makkonen, Katri M., Laitinen, Jarmo T., Tammi, Raija H., Tammi, Markku I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140273/
https://ncbi.nlm.nih.gov/pubmed/24847057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551804
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados