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The regulatory isoform rPGRP-LC resolves immune activation through ESCRT-mediated receptor clearance

The innate immune system needs to distinguish between harmful and innocuous stimuli to adapt immune activation to the level of threat. How Drosophila mounts differential immune responses to dead and live Gram-negative bacteria using the single peptidoglycan receptor PGRP-LC is unknown. We describe a...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Immunol
Asıl Yazarlar: Neyen, Claudine, Runchel, Christopher, Schüpfer, Fanny, Meier, Pascal, Lemaitre, Bruno
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648041/
https://ncbi.nlm.nih.gov/pubmed/27548432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3536
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