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The regulatory isoform rPGRP-LC resolves immune activation through ESCRT-mediated receptor clearance
The innate immune system needs to distinguish between harmful and innocuous stimuli to adapt immune activation to the level of threat. How Drosophila mounts differential immune responses to dead and live Gram-negative bacteria using the single peptidoglycan receptor PGRP-LC is unknown. We describe a...
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出版年: | Nat Immunol |
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主要な著者: | , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648041/ https://ncbi.nlm.nih.gov/pubmed/27548432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3536 |
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