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The regulatory isoform rPGRP-LC resolves immune activation through ESCRT-mediated receptor clearance

The innate immune system needs to distinguish between harmful and innocuous stimuli to adapt immune activation to the level of threat. How Drosophila mounts differential immune responses to dead and live Gram-negative bacteria using the single peptidoglycan receptor PGRP-LC is unknown. We describe a...

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Bibliografski detalji
Izdano u:Nat Immunol
Glavni autori: Neyen, Claudine, Runchel, Christopher, Schüpfer, Fanny, Meier, Pascal, Lemaitre, Bruno
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648041/
https://ncbi.nlm.nih.gov/pubmed/27548432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3536
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