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The regulatory isoform rPGRP-LC resolves immune activation through ESCRT-mediated receptor clearance

The innate immune system needs to distinguish between harmful and innocuous stimuli to adapt immune activation to the level of threat. How Drosophila mounts differential immune responses to dead and live Gram-negative bacteria using the single peptidoglycan receptor PGRP-LC is unknown. We describe a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Immunol
Päätekijät: Neyen, Claudine, Runchel, Christopher, Schüpfer, Fanny, Meier, Pascal, Lemaitre, Bruno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648041/
https://ncbi.nlm.nih.gov/pubmed/27548432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3536
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