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The regulatory isoform rPGRP-LC resolves immune activation through ESCRT-mediated receptor clearance
The innate immune system needs to distinguish between harmful and innocuous stimuli to adapt immune activation to the level of threat. How Drosophila mounts differential immune responses to dead and live Gram-negative bacteria using the single peptidoglycan receptor PGRP-LC is unknown. We describe a...
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| Udgivet i: | Nat Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648041/ https://ncbi.nlm.nih.gov/pubmed/27548432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3536 |
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