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An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication

Here we show that the adenovirus major late promoter produces a 31-nucleotide transcriptional start site small RNA (MLP-TSS-sRNA) that retains the 7-methylguanosine (m7G)-cap and is incorporated onto Ago2-containing RNA-induced silencing complexes (RISC) in human adenovirus-37 infected cells. RNA po...

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Foilsithe in:RNA
Main Authors: Kamel, Wael, Akusjärvi, Göran
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648037/
https://ncbi.nlm.nih.gov/pubmed/28839112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.061291.117
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